Zebrafish

BMP Signaling

Morpheus Model ID: M2982 Persistent identifier for this Morpheus model: Copy Spatio-temporal model of BMP signaling Introduction Juxtaposed sources of bone morphogenetic protein (BMP) and Nodal signaling molecules induce the formation of a full body axis in zebrafish embryos. Soh et al. studied body axis formation in zebrafish by transplanting signaling sources, specifically single clones expressing mouse BMP4 (mBMP4), and thereby inducing a secondary axis.