1D PDE Barkley Model

Derived from the seminal Hodgkin-Huxley and FitzHugh-Nagumo models, the Barkley model is probably the simplest continuous model for excitable media. It replaces the cubic term in the FitzHugh-Nagumo model with a piece-wise linear term as a simplification that enables fast simulation.

Try the Examples

Examples Menu To explore the potential and modeling features, it is the best to learn by example. Morpheus comes with a range of fully functional example models showcasing a number of model formalism and modeling features.

Step-by-Step Example

To show SBML support in Morpheus as of version 2.1 in practice, we give a step-by-step example of how to download, import and extend an SBML model. 1. Get an SBML Model from BioModels First, we browse the BioModels model repository and select a model.

Convert to 2D

Converting the model from the previous chapter into a 2D model is trivial in Morpheus. In the Space section, you only need to change the Size of the Lattice to e.

Coupled ODE Lattice: Lateral Signaling

Morpheus Model ID: M0004 Open in Morpheus History Persistent Identifier Use this permanent link to cite or share this Morpheus model: Copy Introduction This example model cell fate decisions during early patterning of the pancreas (de Back et al.


“How are neighborhoods defined?” Types of Neighborhoods Types of neighborhood are used: Space → Lattice → Neighborhood: This is the default Neighborhood for the lattice. It ist used by the NeighborhoodReporter and fallback for all other Neighborhood definitions.