SBML

Step-by-Step Example

To show SBML support in Morpheus as of version 2.1 in practice, we give a step-by-step example of how to download, import and extend an SBML model. 1. Get an SBML Model from BioModels First, we browse the BioModels model repository and select a model.

Overview

Morpheus supports almost all of the SBML core standard. And has been validated on the extensive SBML test suite.

Conclusion

The improved support for SBML models in Morpheus provides an important interface between single-cell and multi-cell models. Morpheus' capabilities for solving SBML models have been tested and validated extensively using the SBML Test Suite.

Example

Let’s go through an example. We’ll construct a model in which an intracellular cell cycle network (ODE) regulates the division of motile cells which (CPM) release a diffusive cytokine (PDE) which, in turn, controls the cell cycle (ODE).

Morpheus 2.2 Release Notes

New GUI functionalities, better performance with OpenMP parallelization of Mappers and Reporters, improved online courses and much more

Open Source Release Coming Soon!

We are currently preparing a major new release of Morpheus, version 2.0! This release adds transparency, customizability and extensibility. The source code will be distributed under an open source license. Morpheus 2 includes a stable API to enable plugin development.