Reaction-Diffusion

A Word on the Word ‘Multiscale’ First, let’s clarify what we mean by the somewhat hyped term ‘multiscale’. Generally, the term refers to mathematical and computational models that simultaneously describe processes at multiple time and spatial scales.

How does immune cell polarity respond to changing stimuli? Introduction Neutrophils are fast-moving immune cells that polarize and reorient in response to external signals. Using optogenetic control of PI3K, recent experiments revealed that when a localized light stimulus becomes global, cells reverse their polarity — a behaviour not predicted by classical models.