Published Models

Introduction This model combines simple Notch signaling with the cellular Potts model (CPM), which drives cell sorting as a result of differential adhesion. Model details are contained in the reference Mulberry and Keshet, 2020.

Spatio-temporal model of BMP signaling Introduction Juxtaposed sources of bone morphogenetic protein (BMP) and Nodal signaling molecules induce the formation of a full body axis in zebrafish embryos. Soh et al.

Spatio-temporal model of planar polarity regulation during planarian regeneration Introduction This simulation reproduces Figure 4D of the referenced paper. Parameter values correspond to the β-catenin-1(RNAi) pattern as given in Table S2 of the referenced paper.

Spatio-temporal model of planar polarity regulation during planarian regeneration Introduction This simulation reproduces Figure 4C of the referenced paper. Parameter values correspond to the wild type pattern (control) as given in Table S2 of the referenced paper.

Bile Pressure Drives YAP Signaling During Liver Regeneration Introduction During development and regeneration, tissues must grow to the proper size. But tissue growth is just the result of independent cell cycle control systems in the individual cells.