Pattern Formation

Introduction This example model cell fate decisions during early patterning of the pancreas (de Back et al., 2012). The simple gene regulatory network of each cell is coupled to adjacent cells by lateral (juxtacrine) signaling.

Autoregulatory multicellular incoherent feedforward loop (mIFFL) that generates the 7-stripe even-skipped (eve) expression pattern in Drosophila melanogaster embryogenesis Introduction This model demonstrates the influence of maternal effect genes and gap genes on the even-skipped (eve) gene.