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Multicellular Model
Models
Published Models
Worm
Caenorhabditis elegans L1 Aggregation
Morpheus Model ID:
M7683
Introduction Larvae of the nematode Caenorhabditis elegans aggregate into clusters of several hundred moving individuals when starved during their first larval stage (see video below). Avery et al. proposed that starved larvae produce and respond chemotactically to two diffusible chemical signals, a short-range attractant and a longer range repellent.
L. Avery
,
B. Ingalls
,
C. Dumur
,
A. Artyukhin
(Authors)
L. Brusch
(Contributor)
DOI:10.1371/journal.pcbi.1009231
Models
Published Models
Cell Culture
Collective Motion of MDA-MB-231 Breast Cancer Cells
Morpheus Model ID:
M7678
Introduction Collective motion of human breast cancer cells of the cell line MDA-MB-231 was studied by Lee et al. for individual crawling cells, cell doublets, cell quadruplets and for confluent populations on a two-dimensional substrate.
H. G. Lee
,
K. J. Lee
(Authors)
L. Brusch
(Contributor)
DOI:10.1371/journal.pcbi.1009447
Selected Publications
Unraveling the effect of intra- and intercellular processes on acetaminophen-induced liver injury
In high dosages, acetaminophen (APAP) can cause severe liver damage, but susceptibility to liver failure varies across individuals and …
M. M. Heldring
,
A. H. Shaw
,
J. B. Beltman
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