Posts
Events
Download
Models
Overview
Built-in Examples
Contributed Examples
Published Models
Submit Model
Courses
Publications
Support
In-app Docs
FAQ
Wiki
User Forum
Issue Tracker
Bluesky
Light
Dark
Automatic
Morpheus
Morpheus at Recent & Upcoming Events
OpenVT Multicellular Modelling Workshop 2025
Diversity in simulation methods poses challenges in reproducibility, modularity, reusability, and integration within multi-scale simulation. This workshop …
Sun, 13 Jul 2025 09:30 -0600 — 17:00 -0600
Lister Centre, University of Alberta, Edmonton, Canada
Models
Published Models
Cell Culture
Neutrophil Reorientation via Local Feedback and PIP3-Driven Delay
Morpheus Model ID:
M2073
How does immune cell polarity respond to changing stimuli? Introduction Neutrophils are fast-moving immune cells that polarize and reorient in response to external signals. Using optogenetic control of PI3K, recent experiments revealed that when a localized light stimulus becomes global, cells reverse their polarity — a behaviour not predicted by classical models.
J. Algorta
,
J.P. Town
,
O.D. Weiner
,
L. Edelstein-Keshet
(Authors)
Cite
×