GTPase Signaling

Basic Rac-Rho-ECM Spatial Model
Morpheus Model ID: M2061
Introduction This paper describes the regimes of behaviour of a 1D spatial (PDE) model for the mutually antagonistic Rac-Rho GTPases, with feedback to and from the extracellular matrix (ECM). Description The Rac-Rho submodels are bistable, and ECM enhances Rho activation.
E. G. Rens (Contributor)
DOI:10.1088/1478-3975/ac2888
Basic Rac-Rho-ECM Spatial Model
Rac-Rho-ECM Spatial Model with Slip-Bond Integrin Dynamics
Morpheus Model ID: M2062
Introduction This paper describes the regimes of behaviour of a 1D spatial (PDE) model for the mutually antagonistic Rac-Rho GTPases, with feedback to and from the extracellular matrix (ECM). Description The Rac-Rho submodels are bistable, and ECM enhances Rho activation.
E. G. Rens (Contributor)
DOI:10.1088/1478-3975/ac2888
Rac-Rho-ECM Spatial Model with Slip-Bond Integrin Dynamics
Rac-Rho-ECM Spatial Model with Catch-Slip Bond Integrin Biophysics
Morpheus Model ID: M2063
Introduction This paper describes the regimes of behaviour of a 1D spatial (PDE) model for the mutually antagonistic Rac-Rho GTPases, with feedback to and from the extracellular matrix (ECM). Description The Rac-Rho submodels are bistable, and ECM enhances Rho activation.
E. G. Rens (Contributor)
DOI:10.1088/1478-3975/ac2888
Rac-Rho-ECM Spatial Model with Catch-Slip Bond Integrin Biophysics