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The migration of zebrafish polster cells is oriented by the migration of follower cells, allowing robust long-range coordination of different cell populations. Introduction Collective cell migration is an important process during biological development and tissue repair.

Guidance-by-followers combined with one of several simple rule sets for integration of signals from multiple neighbors provides a robust mechanism for collective cell migration. Introduction Collective cell migration is an important process during biological development and tissue repair but may turn malignant during tumor invasion.

This model also requires the separate file boundary.tiff. Introduction The immune system plays an important role in controlling infections and tumors. Knowledge about the mechanisms through which the immune system accomplishes this can be exploited to develop immunotherapies.