E-cadherin

Human iPSC ROCK1-KD : Wildtype Colony Patterning

Morpheus Model ID: M7673 Open in Morpheus History Persistent Identifier Use this permanent link to cite or share this Morpheus model: Copy Introduction Human induced pluripotent stem cells (hiPSCs) can be grown in cell culture where they self-organize spatial patterns.

Human iPSC CDH1-KD : Wildtype Colony Patterning

Morpheus Model ID: M7672 Open in Morpheus History Persistent Identifier Use this permanent link to cite or share this Morpheus model: Copy Introduction Human induced pluripotent stem cells (hiPSCs) can be grown in cell culture where they self-organize spatial patterns.

Human iPSC Wildtype Colony Growth

Morpheus Model ID: M7671 Open in Morpheus History Persistent Identifier Use this permanent link to cite or share this Morpheus model: Copy Introduction Human induced pluripotent stem cells (hiPSCs) can be grown in cell culture where they self-organize spatial patterns.

Two Layer Circuit

Morpheus Model ID: M2051 Open in Morpheus History Persistent Identifier Use this permanent link to cite or share this Morpheus model: Copy Introduction This model combines simple Notch signaling with the cellular Potts model (CPM), which drives cell sorting as a result of differential adhesion.

Three Layer Circuit

Morpheus Model ID: M2052 Open in Morpheus History Persistent Identifier Use this permanent link to cite or share this Morpheus model: Copy Introduction This model combines simple Notch signaling with the cellular Potts model (CPM), which drives cell sorting as a result of differential adhesion.

Single Genotype Circuit

Morpheus Model ID: M2053 Open in Morpheus History Persistent Identifier Use this permanent link to cite or share this Morpheus model: Copy Introduction This model combines simple Notch signaling with the cellular Potts model (CPM), which drives cell sorting as a result of differential adhesion.

Self-organized multicellular structures from simple cell signaling: a computational model

Recent synthetic biology experiments reveal that signaling modules designed to target cell-cell adhesion enable self-organization of multicellular structures [[Toda, 2018](https://science.sciencemag.org/content/361/6398/156.full)]. Changes in …