Cell Polarity

Collective cell migration is an important process during biological development and tissue repair but may turn malignant during tumor …

Parallelization of the CPM simulation, heterogeneous diffusion

The migration of zebrafish polster cells is oriented by the migration of follower cells, allowing robust long-range coordination of different cell populations. Introduction Collective cell migration is an important process during biological development and tissue repair.

Guidance-by-followers combined with one of several simple rule sets for integration of signals from multiple neighbors provides a robust mechanism for collective cell migration. Introduction Collective cell migration is an important process during biological development and tissue repair but may turn malignant during tumor invasion.

Morphogenesis, wound healing, and some cancer metastases depend upon the migration of cell collectives that need to be guided to their …

Spatio-temporal model of planar polarity regulation during planarian regeneration Introduction This simulation reproduces Figure 4D of the referenced paper. Parameter values correspond to the β-catenin-1(RNAi) pattern as given in Table S2 of the referenced paper.

Spatio-temporal model of planar polarity regulation during planarian regeneration Introduction This simulation reproduces Figure 4C of the referenced paper. Parameter values correspond to the wild type pattern (control) as given in Table S2 of the referenced paper.

Polarity is a universal design principle of biological systems that manifests at all organizational scales, yet its coordination across …