Zebrafish

  • Neuromast Regeneration

    Neuromast regeneration in zebrafish larvae with local control of cell proliferation following severe ablation Introduction Neuromasts of zebrafish (Danio rerio) larvae regenerate robustly after the loss of up to 90-95 % of their cells.

  • Pancreas Islet

    How is the right islet size established during zebrafish pancreas development? Introduction Beta cells in the developing pancreas of zebrafish divide rapidly between 5 and 30 days post fertilization (dpf) and additional beta cells are recruited to the islet.

  • Guidance by Followers

    The migration of zebrafish polster cells is oriented by the migration of follower cells, allowing robust long-range coordination of different cell populations. Introduction Collective cell migration is an important process during biological development and tissue repair.

  • Robust Guidance by Followers

    Guidance-by-followers combined with one of several simple rule sets for integration of signals from multiple neighbors provides a robust mechanism for collective cell migration. Introduction Collective cell migration is an important process during biological development and tissue repair but may turn malignant during tumor invasion.

  • NSC in Telencephalon

    Introduction Whether individual stem cell divisions are coordinated or random is important for tissue morphogenesis, homeostasis and tumour growth. Lupperger et al. have analyzed the spatio-temporal division patterns of adult neural stem cells (NSC) in the zebrafish telencephalon.

  • Lateral Line Primordium 1D

    Spatio-temporal model of self-organisation inside the zebrafish posterior lateral line primordium Introduction The zebrafish posterior lateral line primordium is the precursor of the neuromasts, which form sensory organs responding to fluid flow.

  • BMP Signaling

    Spatio-temporal model of BMP signaling Introduction Juxtaposed sources of bone morphogenetic protein (BMP) and Nodal signaling molecules induce the formation of a full body axis in zebrafish embryos. Soh et al.