Naba Mukhtar, Eric N Cytrynbaum, and Leah Edelstein-Keshet (2022) A Multiscale computational model of YAP signaling in epithelial fingering behaviour
This file produced SI Figure 4.
We thank Lutz Brusch for providing a basic cell sheet simulation that we modified and adapted to this project YREsheetFlat2ControlControl(rand_uni(0,1)<0.006*(exp(-time/300)+0.2)) * (cell.center.x<40)Only cells in the first 40 pixels can divide, regardless of domain size. Before, this was size.x*0.1(cell.center.x>0.99*size.x)(ky+kyr*R)*(Ytot-Y) - (kye*Y*E + Dy*Y)C - ke*Y^h/(K^h+Y^h) - De*EalphaR*(Cr + kr*Y^n/(Kr^n+Y^n))*(Rtot-R) - Dr*Rsize.x - cell.center.xavspeed+d.abs*100avspeed/timeavspeed2 + d.abs*100*(time > stoptime-201)avspeed2/20022