Naba Mukhtar, Eric N Cytrynbaum, and Leah Edelstein-Keshet (2022) A Multiscale computational model of YAP signaling in epithelial fingering behaviour
This file produced SI Figure 3.
A few cells with the YAP-Rac-E cadherin circuit governing their motility and adhesion. Model based on
Park, J., Kim, D.H., Shah, S.R., Kim, H.N., Kim, P., QuiƱones-Hinojosa, A. and Levchenko, A., 2019. Switch-like enhancement of epithelial-mesenchymal transition by YAP through feedback regulation of WT1 and Rho-family GTPases. Nature communications, 10(1), pp.1-15.
YREcells2(ky+kyr*R)*(Ytot-Y) - (kye*Y*E + Dy*Y)C - ke*Y^h/(K^h+Y^h) - De*E(Cr + kr*Y^n/(Kr^n+Y^n))*(Rtot-R) - Dr*RCr+0.1*(cell.center.y>0.52*size.y)*(time<2)*(Cr<0.1)avspeed+d.abs*100avspeed/timesize.x - cell.center.x(cell.center.x>0.95*size.x)22