Model ID: https://identifiers.org/morpheus/M5932 File type: Main model Software: Morpheus (open source). Download from: https://morpheus.gitlab.io Full title: Patterned Tissue Growth Regulation along Turing Patterns from Gierer-Meinhardt Model Authors: B. Kaity, D. Lobo Submitter: Y. Korotkyi, G. Börner Curator: J. Bürger Michaelis Date: 07.05.2026 Reference: This model reproduces a published result, originally obtained with a different simulator: B. Kaity, D. Lobo: Emergent stable tissue shapes from the regulatory feedback between morphogens and cell growth. J. Theor. Biol. 620: 112354, 2026. https://doi.org/10.1016/j.jtbi.2025.112354 Comment: Reproduction of Figure 9 from Kaity et al. Turing-driven stable circular tissue shape. Schnakenberg activator-inhibitor system regulates cell growth. Two-stage development: low s (proliferation), then high s (steady state). Length^2 conversion: L2 = A00/pi applied to alpha, q, s (all length^2-bearing quantities).

2 if(time < t_dev, s_dev, s_steady) pi*r^2 Lambda*(q2 + gamma*m2^2*m3 - lambda2*m2 - g*m2) Lambda*(q3 - gamma*m2^2*m3 - lambda3*m3 - g*m3)

reaction_m2 + D_m2 reaction_m3 + D_m3 ((g_max-g_min)*m2^h/(s^h+m2^h)+g_min)*(c^h/(c^h+(neighbor_count*neighbor_correction)^h)) g*r/2 cell.volume >= 2*A00 sqrt(cell.volume/pi) cell.volume <= A00/2

time==10000 and cell.center.x>(size.x*0.6) optimal optimal