Full title: Single Genotype Circuit Authors: N. Mulberry, L. Edelstein-Keshet Contributors: N. Mulberry Date: 24.03.2021 Software: Morpheus (open-source). Download from https://morpheus.gitlab.io Model ID: https://identifiers.org/morpheus/M2053 Reference: N. Mulberry, L. Edelstein-Keshet: Self-organized Multicellular Structures from Simple Cell Signaling: A Computational Model. Phys. Biol. 17: 066003, 2020. https://doi.org/10.1088/1478-3975/abb2dc Comment: Formation of two-layer structure starting from a single genotype. All cells are initially the same, but they specialize into receivers and senders.

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N0*(1+I^p/(I0^p+I^p)) - Kc*N*D - Kt*N*Dn - gamma*N Kt*N*Dn - gammaI*I D0*(I0^p/(I0^p+I^p)) - Kc*N*D - Kt*D*Nn - gamma*D I^p/(I0^p+I^p) - gamma*E 2 6