The explosion in biological data gathering that we have witnessed in the last decades has not alleviated our lack of understanding of how living systems work. There is a perception that theoretical analysis can help to bridge the gap between facts and concepts, and consequently the last few years have witnessed a substantial increase in the number of studies combining experiments and modeling. This conference will be aimed at exploring the key quantitative principles underlying modern biology. The talks and activities within the meeting will examine the extent to which general principles can be used to describe biological systems, in the light of the explosion of quantitative data coming from all corners of biology. To that end, we intend to bring together researchers working on a variety of biological problems from a quantitative perspective, which showcase some of the shared conceptual threads that are used in problems ranging from quantitative immunology to development.