Modeling multicellular systems with Morpheus.
With the increasing availability of quantitative data on multicellular systems and tissues, there is a growing need for computational modeling to gain mechanistic understanding of tissue behavior. Morpheus is a modeling environment for the simulation and integration of cell-based models with ordinary differential equations and reaction-diffusion systems. It enables rapid development of multi-scale models using a declarative modeling language instead of programming code. Moreover, its graphical user interface supports the entire workflow from model construction and simulation to visualization, archiving and batch processing.