A modeling and simulation environment for the study of multi-scale and multicellular systems.
Some of its key features are:
- multi-scale simulation: simulate multi-scale multicellular systems coupling ODEs, PDEs and cellular Potts models in 2D or 3D.
- declarative modelling: construct models by describing them in a GUI instead of programming code.
- MorpheusML language: easily share model description files with collaborators and copy/paste model parts.
- SBML support: import SBML models (e.g. from
BioModels database) into selectable cell types of a multicellular model, over 80% of SBML L3V2 and package comp are supported,
- workflow: tools for data export, visualization and parameter scans.
- automatic scheduling: efficient simulation based on computed model dependency graph and adaptive solvers.
- extensible: customize and extend features by developing your own plugins.
- open-source: source code at
GitLab under BSD license.
- public model repository: share
your models with citable persistent identifier and authorship credit.
- data integration:
FitMultiCell toolbox for efficient parameter estimation from experimental data.
- easy to get started: free
online courses, context-sensitive in-app documentation, rich in-app examples menu, interactive model graph display.
Morpheus is developed by
Jörn Starruß (
Walter de Back (
at the Center for Information Services and High Performance Computing, TU Dresden, Germany.
Morpheus development is supported by
- DFG Research Software Sustainability programme (e-Research Technologies)
- BMBF e:Med Systems Medicine network
- BMBF Computational Life Sciences